関連する実験動画
Updated: Mar 1, 2026

06:36
Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
Published on: May 1, 2019
7.5K
びまん性消化管浸潤を呈した低分化型腺癌の1例
Wei Gao1, Yusheng Yang2, Xinyi Hu1
1Department of Gastroenterology, Songjiang Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No. 746, Zhongsanzhong Road, Songjiang District, Shanghai, 201600, China.
Discover oncology
|February 28, 2026
まとめ
64歳男性の消化管全体にびまん性に浸潤した低分化型癌(PCC)の稀な症例。この攻撃的な癌は胃と十二指腸の病変を呈し、包括的な診断評価の重要性を強調しています。
科学分野:
- 消化器病学;腫瘍学;病理学
背景:
- 胃癌は世界的な健康問題であり、世界で4番目に多い癌死の原因となっている。64歳男性が食後の臍周囲痛を呈し、消化管病変の可能性を示唆した。
研究 の 目的:
- 消化管全体にびまん性に浸潤した低分化型癌(PCC)の極めて稀な症例を報告する。この稀な悪性腫瘍の診断上の課題と組織学的特徴を強調する。
主な方法:
- 腹部の造影CT検査。食道胃十二指腸内視鏡検査および大腸内視鏡検査。確定診断のためのヘマトキシリン・エオジン(HE)染色および免疫組織化学的分析。
主要な成果:
- CT検査では胃前庭部の肥厚とリンパ節腫大が明らかになった。内視鏡検査では、胃と十二指腸に腫瘍性病変が確認され、回腸と結腸には炎症性変化の可能性がある。組織病理学的検査により、消化管全体にびまん性粘膜インプラントを伴う低分化型浸潤性腺癌と診断され、低分化型癌(PCC)と診断された。
結論:
- 低分化型癌(PCC)は腺癌の悪性度の高いサブタイプである。PCCによる消化管全体のびまん性浸潤は例外的に稀であり、診断および治療上の課題をもたらす。
関連する概念動画
Histology of the Gastrointestinal (GI) Tract
4.0K
The GI tract, from beginning to end, is made up of four continuous tissue layers that adjust their structure according to their specific roles. These layers, from innermost to outermost, are known as the mucosa, submucosa, muscularis, and serosa, which are continuous with the mesentery.
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
4.0K
Inflammatory Bowel Disease II: Crohn's Disease
1.4K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.4K
Chronic Bowel Disorders: Introduction
855
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
855
Barrett Esophagus-II: Clinical Manifestations and Management
1.3K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.3K
Inflammatory Bowel Disease I: Ulcerative Colitis
1.3K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.3K
