思春期におけるクリゾチニブ関連結節性強膜炎
Mennatullah Elfwwal1, Douglas S Hawkins2, Laura C Huang1
1Department of Ophthalmology, University of Washington, Seattle, Washington; Division of Ophthalmology, Seattle Children's Hospital, Seattle, Washington.
Abstract:
We report the case of a 17-year-old girl with history of anaplastic large-cell lymphoma on crizotinib therapy who presented with pain and blurred vision in the left eye. Examination demonstrated nodular non-necrotizing anterior scleritis in the left eye. The patient initially improved with oral glucocorticoid treatment until she developed nodular non-necrotizing anterior scleritis in the right eye during taper of this medication. Discontinuation of crizotinib allowed the patient to taper off glucocorticoid treatment, with subsequent resolution of scleritis.
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