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Updated: Aug 18, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
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ティオグアニンは,慢性粒細胞性白血病の主要な治療法として使用されています

A S Spiers, D A Galton, J Kaur

    Lancet (London, England)
    |April 12, 1975
    PubMed
    まとめ

    ティオグアニンの治療は,慢性粒細胞性白血病 (C.G.L.) に対して調査されました. フィラデルフィア染色体 (Ph-1) の陽性を減らすために. 寛解やPh-1ネガティビティは得られなかったが,チオグアニンはブスルファンと同等の有効性を示し,副作用は逆転可能であり,さらなる研究が必要である.

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