関連する実験動画
Updated: Aug 18, 2026

08:04
Murine Fetal Echocardiography
Published on: February 15, 2013
まとめ
この研究では,心室隔膜欠陥による肺動脈縮を調査し,全身側動脈 (Systemic Collateral Arteries, SCA) が肺循環を供給できることを発見しました. SCA帯状の早期介入は,乳児の肺血管を保護する可能性があります.
科学分野:
- ペディアトリック・カルディオロジー
- 胸部外科手術について
- 心血管病理学 心血管病理学
背景:
- 心室隔膜欠陥 (PA-VSD) による肺動脈縮症は,肺動脈の発達において複雑な課題を提示する.
- 系統側動脈 (SCAs) の役割を理解することは,PA-VSDにおける肺血流の管理に極めて重要です.
研究 の 目的:
- 22個のPA-VSDサンプルを組織学的に分析する.
- 主肺動脈を特徴付け,SCAとダクトス動脈を区別し,副循環を評価する.
- ディスタル肺血管床の形状を評価するために.
主な方法:
- 22個のPA-VSD標本の組織学的検査.
- 肺動脈の主動脈の存在と胞分離の評価.
- SCAと全身動脈のヒストロジカル比較.
- コントラスト材料の注入は,付随容器の機能を実証します.
主要な成果:
- 3例で主肺動脈の欠損が確認された.
- SCAsは,全身動脈に似た組織学的特徴を示しています.
- SCAsは機能的であると確認され,遠隔肺動脈を供給しています.
- ディスタル肺床を perfusing 大きなSCAsは,増殖性病変につながる可能性があります.
結論:
- 主肺動脈の欠損は,PA-VSDおよび持続性トランクス動脈症で発生することがあります.
- SCAsは,PA-VSDにおける肺循環に機能的な役割を果たします.
- SCAsの早期帯びは,遠隔肺血管系を保護する可能性があります; シャントを防ぐために,修復中の結合が推奨されます.
関連する概念動画
Overview of Systemic and Pulmonary Circulation
The systemic and pulmonary circuits are crucial components of the circulatory system, working together to transport blood between the heart, lungs, and the rest of the body. The process begins with pulmonary circulation, where deoxygenated blood is pumped from the right ventricle to the lungs via the pulmonary trunk and arteries. Upon reaching the lungs, the blood becomes oxygenated and returns to the heart, specifically to the left atrium, via the pulmonary veins.
The oxygenated blood is sent...
The oxygenated blood is sent...
Coronary Circulation
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Development of the Heart
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
Overview of Pulmonary Circulation
The pulmonary circulation is a vital system in our body that acts as a bridge between the respiratory and cardiovascular systems. It serves as a transport network for deoxygenated blood from the heart to the lungs and then returns oxygen-rich blood back to the heart.
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
Fetal Circulation
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Pulmonary Hypertension: Classification and Pathogenesis
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
There are various classifications for PH, each relating to different underlying causes and also...

