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Updated: Jul 17, 2026

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
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ポリオウイルスによる転写因子の活性抑制

N Crawford1, A Fire, M Samuels

  • 1Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139.

Cell
|December 1, 1981
PubMed
まとめ

ポリオウイルス感染症は,重要な転写因子を枯渇させることにより,宿主細胞RNA合成を阻害する. この研究では,感染した細胞抽出物にはRNAポリメラーゼIIに必要な成分が欠けていて,DNA転写に影響を及ぼすことがわかりました.

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