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Updated: Jun 17, 2026

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites
09:31

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites

Published on: March 22, 2016

推定乳がん腫瘍遺伝子int-1の構造と核酸配列;プロウイルス挿入は,タンパク質エンコードドメインを無傷にします

A van Ooyen, R Nusse

    Cell
    |November 1, 1984
    PubMed
    まとめ

    マウス乳腺腫瘍ウイルス (MMTV) のプロウイルス挿入は,乳腺腫瘍の発達に不可欠なint-1腫瘍遺伝子を活性化します. この研究は,int-1遺伝子の構造とそのタンパク質を詳細に説明し,腫瘍発生におけるその役割を確認しました.

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