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Updated: Jul 23, 2026

Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs
08:13

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Published on: December 27, 2016

ミトゲンは,チモサイト内のフォスホイノシチドのリン酸化を増加させます

M V Taylor, J C Metcalfe, T R Hesketh

    Nature
    |November 5, 1984
    PubMed
    まとめ

    リガンド受容体相互作用は,フォスファディチルイノシトール4,5-ビスホスファートの分解と再合成を誘発する. TPA,A23187,Con Aのようなミトゲンは,マウスのチモサイトでフォスファディチリノシトールのリン酸化を増加させ,共通のシグナル伝達経路を示唆する.

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