都市部と部族のアフリカにおける血圧とその相関値

P S Sever, D Gordon, W S Peart

Lancet (London, England)

|July 12, 1980

まとめ

都市部のクソサ族の人口は,部族集団と比較して高血圧と肥満を示しています. 都市化,ダイエット,肥満は高血圧に寄与しているように見えますが,低血レニンは遺伝的かもしれません.

科学分野:

心血管の健康についてです.
アントロポロジー人類学
公衆衛生は公衆衛生である.

背景:

都市化が健康に重大な影響を及ぼし,様々な集団で血圧上昇が観察されています.
特定の民族集団における高血圧に影響を与える要因を理解することは,標的を絞った介入に不可欠です.

研究の目的:

南アフリカの部族と都市部のXhosaの人々の血圧と関連する要因を比較するために.
高血圧の違いにおける肥満,食事,生理学的マーカーの役割を調査する.

主な方法:

血圧,肥満指数 (体重,皮膚の厚さ,体重指数),および食中のナトリウム摂取量の比較分析.
尿中のナトリウム/クレアチニン比,プラズマ・ノラドレナリン,プラズマ・レニン活性度の測定.

主要な成果:

都市部のクソサ族は,部族のクソサ族よりも血圧と肥満の指数がかなり高かった.
都市部に住む人々の食事と尿中のナトリウムの値が高く見られたが,グループ内の血圧と直接的な相関は認められなかった.
プラズマ・ノルアドレナリンとプラズマ・レニンの活性性は類似しており,低プラズマ・レニンは一般的で潜在的に遺伝的である.

結論:

都市化は,Xhosaの人口の高血圧と肥満に関連しています.
都市部ではナトリウム摂取量が高くても,ダイエットと肥満は高血圧に大きく寄与しているようです.
遺伝的要因は,ライフスタイルの変化とは無関係に,血レニンのレベルに影響を与える可能性があります.

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