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Updated: May 5, 2026

Purification of Tubulin with Controlled Posttranslational Modifications and Isotypes from Limited Sources by Polymerization-Depolymerization Cycles
07:54

Purification of Tubulin with Controlled Posttranslational Modifications and Isotypes from Limited Sources by Polymerization-Depolymerization Cycles

Published on: November 5, 2020

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非ポリマー化されたチューブリンは,チューブリンmRNAsのレベルを調節する

D W Cleveland, M A Lopata, P Sherline

    Cell
    |August 1, 1981
    PubMed
    まとめ

    チューブリンタンパク質合成は,ミクロチューブルの組み立てが阻害され,チューブリンmRNAレベルが低下したため,急速に減少します. これは,細胞がmRNAの転写と安定性を調節することによってチューブリンレベルを制御することを示唆しています.

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