性線維症患者の間で pseudomonasのクロス感染が発生していますか
Lancet (London, England)
|September 25, 1982
まとめ
環境への曝露は,システィック線維症 (CF) 患者におけるPseudomonas aeruginosa菌株の主要な源である. CF患者間の重大な交叉感染は,長時間,密接な接触を必要とする.
科学分野:
- 医学微生物学 医学微生物学
- 感染症 感染症は感染症です.
- 肺内科 肺内科 肺内科
背景:
- Pseudomonas aeruginosaは,システィック線維症 (CF) 患者における重要な機会性病原体である.
- P. aeruginosaの伝播ダイナミクスを理解することは,CFのケアにおける感染制御に不可欠です.
研究 の 目的:
- 性線維症患者のP. aeruginosa呼吸道感染症の発生源と伝播パターンを調査する.
- P. aeruginosaのコロニー化における環境獲得と患者との接触の役割を決定する.
主な方法:
- CF患者からのP. aeruginosa単離の細菌タイプ化が12ヶ月間にわたって行われました.
- 菌株の差異化のために,血清学とピオシン生産を活用した.
- 患者との接触レベルと家族関係と相関した菌株データ.
主要な成果:
- 1つのP. aeruginosa菌株は,関係のない4人の患者で特定され,環境獲得を示唆しました.
- 6組の兄弟姉妹は同一の菌株を共有したが,兄弟姉妹の間の菌株は異なっていた.
- 接触していない患者の間で広範囲にわたるクロス感染の証拠は見つかりませんでした.
結論:
- 環境は,CF患者をコロニー化するP. aeruginosa菌株の主な源であるようです.
- 性線維症患者の間での交叉感染は,長時間および親密な接触を必要とします.
- 環境の監視と制御措置は,CFの環境におけるP. aeruginosaの管理に不可欠である可能性があります.
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