継続的な外来腹腔内透析における腹腔内炎. 実験室および臨床試験
Lancet (London, England)
|December 18, 1982
まとめ
継続的な外来腹膜透析 (CAPD) は,腹膜炎の発生率を大幅に低下させ,患者の83%が抗生物質で治療に成功しました. しかし,腹膜炎は依然としてCAPDのための適切な施設を必要とする主要な合併症です.
科学分野:
- ネフロロジーは腎臓科
- 感染症 感染症は感染症です.
- 内科内科は,内科の内科である.
背景:
- 継続的外来腹膜透析 (CAPD) は,末期腎疾患の治療法である.
- 炎は,CAPDに関連した重大な合併症であり,患者のアウトカムに影響を及ぼします.
- 抗生物質療法は,CAPDに関連した膜炎の主要な治療法です.
研究 の 目的:
- CAPD患者における炎の発生率と治療結果を3年間の期間で評価する.
- CAPDの腹膜炎の管理において,抗生物質療法,特に腹膜内セフロキシムの有効性を評価する.
- 腹膜炎がCAPDの失敗率と入院率に及ぼす影響を分析する.
主な方法:
- 1979年から1981年の間にCAPDを受けた82人の患者の遡及的分析.
- 周周炎エピソードの追跡,治療戦略,患者のアウトカム.
- クロストリジウム難性大腸炎などの合併症のモニタリングと,抗生物質政策の変更.
主要な成果:
- 炎の発生率は,患者週20人に1回の発生から患者週37人に1回の発生に減少しました.
- 炎136例のうち83%が抗生物質で成功し,62%が内セフロキシムで成功しました.
- 患者の16%が腹膜炎によるCAPD障害を経験し,入院期間は平均4.3日/患者/年であった.
結論:
- CAPDにおける炎の発生率を大幅に減らすことができます.
- 内セフロキシムは,CAPD炎の効果的な治療法ですが,全体的な炎は依然として課題です.
- 適切な施設と改訂された抗生物質政策 (例えば,ネチルミシンとバンコミシン) は,CAPDにおける炎の合併症を最小限に抑えるために不可欠です.
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