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Updated: Jul 30, 2026

An Ex vivo Model to Study Hormone Action in the Human Breast
12:31

An Ex vivo Model to Study Hormone Action in the Human Breast

Published on: January 8, 2015

プロゲスタゲン"効力"と乳がん

G I Swyer

    Lancet (London, England)
    |December 17, 1983
    PubMed
    まとめ

    No abstract available in PubMed .

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    Last Updated: Jul 30, 2026

    An Ex vivo Model to Study Hormone Action in the Human Breast
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    Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
    These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...

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