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Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
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Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity

Published on: September 16, 2011

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表面免疫グロブリンによる細胞活性化と無敏感化のモデル:ヒトベースフィルからヒスタミンが放出されるケース

M Dembo, B Goldstein

    Cell
    |November 1, 1980
    PubMed
    まとめ

    この研究では,ヒトのベースフィール細胞から免疫グロブリンE (IgE) 媒介によるヒスタミン放出がどのように制御されるかをモデル化しています. 特定の非特定の無敏感化,抗原過剰抑制を説明し,ヒスタミン放出に対するカルシウムとIgEレベルの影響を予測する.

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