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Updated: Jul 21, 2026

CRISPR-Mediated Reorganization of Chromatin Loop Structure
09:20

CRISPR-Mediated Reorganization of Chromatin Loop Structure

Published on: September 14, 2018

染色体構造の変化によって媒介される変異遺伝子発現の調節

R L Davies, S Fuhrer-Krusi, R S Kucherlapati

    Cell
    |December 1, 1982
    PubMed
    まとめ

    遺伝子発現は,クロマチンの構造の変化により,急速に切り替えることができます. この研究では,マウス細胞におけるヘルペス・シンプレックスウイルスチミジンキナーゼ (HSV-tk) 遺伝子の高頻度スイッチングが観察され,クロマチンのアクセシビリティに関連していた.

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