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Updated: Aug 12, 2026

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
11:48

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

Published on: October 9, 2014

5つのクローンされたベータタラセミア遺伝子の特異的な転写およびRNAスプライシングの欠陥

R Treisman, S H Orkin, T Maniatis

    Nature
    |April 14, 1983
    PubMed
    まとめ

    この研究は,β-タラセミア遺伝子の特定の突然変異が遺伝子転写とRNAスプライシングをどのように破壊するかを明らかにしています. これらの遺伝的欠陥は,転写レベルを低下させ,異常なRNAを引き起こし,ベータ・グロービンの生成に影響を及ぼします.

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