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Updated: Aug 4, 2026

A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins
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A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins

Published on: May 29, 2016

インフルエンザにおける単一アミノ酸置換は,ヘマグルーチニンの受容体結合特異性を変化させます

G N Rogers, J C Paulson, R S Daniels

    Nature
    |July 7, 1983
    PubMed
    まとめ

    インフルエンザウイルスのヘマグルチニン (HA) は,シアル酸受容体を通して細胞に結合する. HA1の位置226にある特定のアミノ酸の変化により,ウイルスがNeuAc alpha 2-3GalまたはNeuAc alpha 2-6Gal結合に結合するかどうかを決定します.

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