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Updated: May 5, 2026

Targeted DNA Methylation Analysis by Next-generation Sequencing
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Published on: February 24, 2015

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CpGを含む制限部位は,ヒトDNAのポリモルフィズムがより高い頻度を示しています

D Barker, M Schafer, R White

    Cell
    |January 1, 1984
    PubMed
    まとめ

    研究者らは,制限酵素を使用して,制限断片長ポリモルフィズム (RFLP) を検出するために,遺伝的変異を特定しました. CpG配列のメチル化サイトシンは,ヒトDNA,特にMsp IおよびTaq I酵素の変異ホットスポットであることが判明しました.

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