関連する実験動画

Updated: Aug 16, 2026

Mouse Models Of Helicobacter Infection And Gastric Pathologies
07:43

Mouse Models Of Helicobacter Infection And Gastric Pathologies

Published on: October 18, 2018

ネズミの胃酸分泌のオントジェニー:複数の応答システムの証拠

S H Ackerman

    Science (New York, N.Y.)
    |July 2, 1982
    PubMed
    まとめ

    若いラットでは,ペンタガストリンとコレリン作用剤は,ヒスタミン系が機能する前に胃酸の分泌を刺激します. この初期の酸の生成経路は,ヒスタミンの作用とは独立して動作する.

    さらに関連する動画

    A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System07:32

    A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System

    Published on: August 30, 2019

    Profiling Luminal pH in Three-Dimensional Gastrointestinal Organoids Using Microelectrodes08:24

    Profiling Luminal pH in Three-Dimensional Gastrointestinal Organoids Using Microelectrodes

    Published on: July 5, 2024

    関連する概念動画

    What is Monogastric Digestion?01:50

    What is Monogastric Digestion?

    The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
    Hormonal Regulation01:40

    Hormonal Regulation

    Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
    Stomach pH Regulation01:21

    Stomach pH Regulation

    The human body carefully regulates the internal pH of different organs to maintain homeostasis. For example, while the blood plasma maintains a neutral pH of 7, the stomach lumen has an acidic pH of 1.5 - 3.5. The low pH of stomach lumen helps kill pathogens in the food and break down complex food molecules.
    The acid-secreting gastric mucosal epithelial cells (parietal cells) lining the stomach lumen maintain the low pH in the lumen. Numerous ion transporters and channels on these parietal...
    Pathophysiology of Peptic Ulcer Disease: Injurious Factors01:22

    Pathophysiology of Peptic Ulcer Disease: Injurious Factors

    Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
    In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds to M3...
    Mucosal Barrier of the Stomach01:25

    Mucosal Barrier of the Stomach

    The gastric glands contain parietal cells that secrete hydrochloric acid (HCl) for digestion. The cells secrete HCl because it is highly corrosive and essential for breaking down food. To achieve this, they secrete hydrogen and chloride ions into the lumen of the gastric glands, which combine to form HCl.
    Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...
    Gastritis II: Pathophysiology01:26

    Gastritis II: Pathophysiology

    The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...