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Updated: Jul 27, 2026

Examination of Thymic Positive and Negative Selection by Flow Cytometry
14:29

Examination of Thymic Positive and Negative Selection by Flow Cytometry

Published on: October 8, 2012

自己抗原に対する耐性がMHCに制限されているというインビトロ研究からの証拠

H G Rammensee, M J Bevan

    Nature
    |April 19, 1984
    PubMed
    まとめ

    成熟したT細胞は,自己メジャーヒストコンパティビリティコンプレックス (MHC) 分子を持つ外来抗原を認識します. この研究では,T細胞が外来MHC分子との自己抗原を認識することを発見し,T細胞の発達と自己耐性中にMHCの制限を示唆しました.

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