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Updated: Jul 28, 2026

Engineering and Evolution of Synthetic Adeno-Associated Virus (AAV) Gene Therapy Vectors via DNA Family Shuffling
21:55

Engineering and Evolution of Synthetic Adeno-Associated Virus (AAV) Gene Therapy Vectors via DNA Family Shuffling

Published on: April 2, 2012

SV40とマウスベータグロービンの基因キメラが転写され,適切にスプライスされます

G Chu, P A Sharp

    Nature
    |January 29, 1981
    PubMed
    まとめ

    科学者たちは,猿のウイルス40 (SV40) とマウスのβ-グロービン配列を組み合わせた遺伝子キメラを作成しました. このエンジニアリングされた遺伝子は,猿の細胞における異なる遺伝子要素の間のスプライシングを成功裏に実証し,種間の遺伝子スプライシングが可能であることを証明しました.

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