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Updated: Jul 21, 2026

Light/dark Transition Test for Mice
10:35

Light/dark Transition Test for Mice

Published on: November 13, 2006

イソタイプスイッチングは,ネズミのpre-B細胞系におけるイソタイプスイッチングである.

S Akira, H Sugiyama, N Yoshida

    Cell
    |September 1, 1983
    PubMed
    まとめ

    アイソタイプスイッチングは,CH遺伝子の削除によって,前B細胞で発生し,スイッチ領域を必要としません. このプロセスは,V領域の形成前に起こりうるので,先行するMu鎖の表現が示される.

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    Forced Transdifferentiation01:28

    Forced Transdifferentiation

    Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
    Artificial transdifferentiation occurs...