関連する実験動画

Updated: Jul 15, 2026

Recombinant Retroviral Production and Infection of B Cells
09:19

Recombinant Retroviral Production and Infection of B Cells

Published on: February 18, 2011

バクテリア遺伝子のレトロウイルスの移転がマウスの血球形成原始細胞に起こる

A Joyner, G Keller, R A Phillips

    Nature
    |October 6, 1983
    PubMed
    まとめ

    研究者らはレトロウイルスベクトルを用いて,薬剤耐性遺伝子をマウスの血液生成原始細胞に転送した. この技術は,血液細胞の発達および関連する疾患に関する分子遺伝学的研究を進めています.

    さらに関連する動画

    Mouse Genome Engineering Using Designer Nucleases12:04

    Mouse Genome Engineering Using Designer Nucleases

    Published on: April 2, 2014

    Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm08:12

    Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm

    Published on: December 22, 2016

    関連する概念動画

    In-vitro Mutagenesis01:16

    In-vitro Mutagenesis

    To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
    Bacterial Transformation01:33

    Bacterial Transformation

    In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
    Mutations in Microorganisms01:18

    Mutations in Microorganisms

    Mutations are heritable changes in an organism’s genome involving alterations in the base sequence of DNA or RNA. These changes can influence cellular processes and phenotypic traits, potentially transforming the unaltered wild type into a mutant form. Such changes, termed forward mutations, are pivotal in shaping the genetic diversity of organisms.RNA viruses exhibit the highest mutation rates due to the absence of robust proofreading mechanisms during genome replication. In contrast,...
    Transduction01:16

    Transduction

    Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome are...