関連する実験動画

Updated: Jul 16, 2026

Double Whole Mount in situ Hybridization of Early Chick Embryos
15:42

Double Whole Mount in situ Hybridization of Early Chick Embryos

Published on: October 27, 2008

鶏の成人ベータグロービン遺伝子の5'端のDNAコンフォーム

J M Nickol, G Felsenfeld

    Cell
    |December 1, 1983
    PubMed
    まとめ

    この研究では,鶏のベータ・グロービン遺伝子の過敏領域のDNA構成を調べました. メチル化はDNAの構造を変化させなかったが,デオキシグアノシン経路内で重要な切断部位が見つかった.

    さらに関連する動画

    Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model09:23

    Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model

    Published on: July 29, 2012

    Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples12:47

    Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples

    Published on: August 29, 2017

    関連する概念動画

    Protein Organization01:13

    Protein Organization

    Overview
    Protein and Protein Structure02:15

    Protein and Protein Structure

    Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
    A protein's shape is critical to its function. For example, an enzyme can...
    Position-effect Variegation02:32

    Position-effect Variegation

    In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
    Protein Organization01:24

    Protein Organization

    Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
    The primary structure of a protein is its amino acid sequence.
    General Transcription Factors01:30

    General Transcription Factors

    Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
    Bacterial Protein Maturation01:26

    Bacterial Protein Maturation

    Bacterial protein maturation is a tightly regulated process that ensures newly synthesized polypeptides achieve correct functional conformations. This maturation involves a series of modifications, folding events, and quality control steps, often assisted by specialized chaperone proteins.N-Terminal ModificationsThe maturation of bacterial polypeptides begins cotranslationally as the polypeptide exits the ribosome. The first amino acid, N-formylmethionine (fMet), is typically modified at the...