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Updated: Jul 30, 2026

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
07:13

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer

Published on: March 26, 2014

ネズミの染色体15の推定乳がん腫瘍遺伝子 (int-1) のプロウイルス活性化モード

R Nusse, A van Ooyen, D Cox

    Nature
    |January 12, 1984
    PubMed
    まとめ

    マウス乳腺腫瘍ウイルス (MMTV) は,int-1遺伝子付近でproviral挿入を介してマウスの乳腺がんを誘発する. この挿入は,潜在的腫瘍遺伝子のint-1遺伝子を腫瘍に活性化しますが,正常な組織にはそうではありません.

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