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Updated: Aug 5, 2026

Studying the Stoichiometry of Epidermal Growth Factor Receptor in Intact Cells using Correlative Microscopy
09:16

Studying the Stoichiometry of Epidermal Growth Factor Receptor in Intact Cells using Correlative Microscopy

Published on: September 11, 2015

エピダーマルの成長因子受容体とv-erb-B腫瘍遺伝子のタンパク質配列の密接な類似性

J Downward, Y Yarden, E Mayes

    Nature
    |February 9, 1984
    PubMed
    まとめ

    鳥類のエリトブロブラストーシスウイルス (AEV) の変形タンパク質v-erb-Bは,ヒトの表皮成長因子 (EGF) 受容体ペプチドと有意な配列の類似性を共有しています. これは,AEVが EGF受容体遺伝子を切り離し,細胞変異に寄与した可能性があることを示唆しています.

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