関連する実験動画

Updated: Aug 7, 2026

Functional Calcium Imaging in Developing Cortical Networks
16:33

Functional Calcium Imaging in Developing Cortical Networks

Published on: October 22, 2011

脳からの電圧依存カルシウムチャネルが平面性脂質二重層に組み込まれています

M T Nelson, R J French, B K Krueger

    Nature
    |March 1, 1984
    PubMed
    まとめ

    この研究では,ネズミの脳からの電圧依存カルシウムチャネルを調査した. 結果は,二価カチオンの種類がチャネル伝導率と開閉時間の両方に影響することを明らかにし,バリウムは最短の平均開閉時間を示しています.

    さらに関連する動画

    Culture of Brain Capillary Pericytes for Cytosolic Calcium Measurements and Calcium Imaging Studies09:33

    Culture of Brain Capillary Pericytes for Cytosolic Calcium Measurements and Calcium Imaging Studies

    Published on: May 27, 2020

    Visualizing Shifts on Neuron-Glia Circuit with the Calcium Imaging Technique11:41

    Visualizing Shifts on Neuron-Glia Circuit with the Calcium Imaging Technique

    Published on: April 8, 2022

    関連する概念動画

    Ion Channels01:19

    Ion Channels

    The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
    Ion channels are specialized integral membrane proteins on the plasma membrane that allow specific...
    The Role of Ion Channels in Neuronal Computation01:19

    The Role of Ion Channels in Neuronal Computation

    A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
    Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential.
    Ligand-gated Ion Channels01:19

    Ligand-gated Ion Channels

    Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
    Three Subfamilies of Ligand-gated Ion Channels
    Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that include the...
    Feedback Regulation of Calcium Concentration01:27

    Feedback Regulation of Calcium Concentration

    Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
    Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...
    Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

    Ligand-Gated Ion Channel Receptor: Gating Mechanism

    Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
    Ligand-gated Ion Channels01:19

    Ligand-gated Ion Channels

    Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
    Three Subfamilies of Ligand-gated Ion Channels
    Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that include the...