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Updated: May 2, 2026

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
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Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

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SV40 T抗原遺伝子を宿すトランス遺伝子マウスは,特徴的な脳腫瘍を発症する

R L Brinster, H Y Chen, A Messing

    Cell
    |June 1, 1984
    PubMed
    まとめ

    SV40早期領域遺伝子を持つトランス遺伝子マウスは脳腫瘍を発症し,遺伝子活性化が腫瘍発生に不可欠であることを示しています. DNA分析は,腫瘍組織におけるSV40遺伝子の再編成と増幅を明らかにしています.

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