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Updated: Oct 3, 2026

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
11:33

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking

Published on: December 17, 2013

Escherichia coliのプロリポタンパク質のシグナルペプチド割れに関する要件

S Inouye, C P Hsu, K Itakura

    Science (New York, N.Y.)
    |July 1, 1983
    PubMed
    まとめ

    グリシンをアラニンに置き換えることで,Escherichia coliのリポプロテインシグナルペプチド分裂部位を変更しても,シグナルペプチド処理を妨げることはありませんでした. しかし,グリシン残基を削除すると,シグナルペプチドの割れが防止され,プロリポタンパク質の適切な処理のためにこの場所での構造的整合性の必要性を強調しました.

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