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Updated: Oct 12, 2026

Coculture Analysis of Extracellular Protein Interactions Affecting Insulin Secretion by Pancreatic Beta Cells
05:51

Coculture Analysis of Extracellular Protein Interactions Affecting Insulin Secretion by Pancreatic Beta Cells

Published on: June 15, 2013

インスリン受容体の抗血清と植物性レクチンは,核包膜のリン酸化にインスリンが及ぼす直接的な効果を模倣する

F Purrello, D B Burnham, I D Goldfine

    Science (New York, N.Y.)
    |July 29, 1983
    PubMed
    まとめ

    インスリンは,ネズミの肝臓の核包膜におけるタンパク質のリン酸化を直接抑制する. インスリン受容体抗血清や植物レクチンなどの薬剤も,この効果を模倣し,インスリンによる直接的な核調節を示唆しています.

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