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Updated: Jul 10, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
13:55

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization

Published on: February 3, 2013

ラムダ2免疫グロブリン鎖の分泌は,その変数領域における単一のアミノ酸置換によって防止されます

G E Wu, N Hozumi, H Murialdo

    Cell
    |May 1, 1983
    PubMed
    まとめ

    ラムダ2光鎖の1つのアミノ酸がグリシンからアルギニンに変化すると,その分泌が防止されます. 免疫グロブリンA (IgA) 骨髄腫細胞の変数領域におけるアルギニンに対するこのグリシン置換は,タンパク質輸出に影響を与えます.

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