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Updated: Apr 30, 2026

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
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ベータ・ラクタマースの分泌には,タンパク質のカルボキシ末端が必要です

D Koshland, D Botstein

    Cell
    |July 1, 1980
    PubMed
    まとめ

    ベータ・ラクタマースのカルボキシ・ターミナル配列は,サルモネラ・タイフィムリウム (Salmonella typhimurium) でその分泌に不可欠である. 機能的な信号配列であっても,完全なタンパク質合成を妨げる突然変異は,β-ラクタマース輸送を阻害する.

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