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Updated: Jul 17, 2026

Quantification of Intracellular Growth Inside Macrophages is a Fast and Reliable Method for Assessing the Virulence of Leishmania Parasites
10:01

Quantification of Intracellular Growth Inside Macrophages is a Fast and Reliable Method for Assessing the Virulence of Leishmania Parasites

Published on: March 16, 2018

メトトレキサート耐性リーシュマニアの不安定なDNA増幅は,安定化中に転位する染色体外円で構成されています

S M Beverley, J A Coderre, D V Santi

    Cell
    |September 1, 1984
    PubMed
    まとめ

    メソトレキサート耐性リーシュマニア・トロピカは,DNA増幅を行い,不安定な円形DNAを形成し,薬物の選択により染色体配列に安定します. このプロセスは,哺乳類の細胞で見られる遺伝子増幅を反映しています.

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