関連する実験動画

Updated: May 5, 2026

Examination of the Telomere G-overhang Structure in Trypanosoma brucei
15:25

Examination of the Telomere G-overhang Structure in Trypanosoma brucei

Published on: January 27, 2011

13.7K

トライパノソーマ・ブルセイの染色体の再編成

L H Van der Ploeg, A W Cornelissen, P A Michels

    Cell
    |November 1, 1984
    PubMed
    まとめ

    トリパノソーマ・ブルセイ (T. brucei) の染色体の再編成は頻繁に起こり,染色体の大きさを変化させ,表面抗原の遺伝子発現に潜在的に影響を与える. これらの変化は,標準的な遺伝子解析によって見逃されることがあります.

    さらに関連する動画

    High-throughput Gene Tagging in Trypanosoma brucei11:26

    High-throughput Gene Tagging in Trypanosoma brucei

    Published on: August 12, 2016

    9.4K
    Detection of Trypanosoma brucei Variant Surface Glycoprotein Switching by Magnetic Activated Cell Sorting and Flow Cytometry09:45

    Detection of Trypanosoma brucei Variant Surface Glycoprotein Switching by Magnetic Activated Cell Sorting and Flow Cytometry

    Published on: October 19, 2016

    8.5K

    関連する概念動画

    Lampbrush Chromosomes01:51

    Lampbrush Chromosomes

    In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
    LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
    7.1K
    Polytene Chromosomes02:04

    Polytene Chromosomes

    Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also...
    9.3K
    Conservative Site-specific Recombination and Phase Variation02:53

    Conservative Site-specific Recombination and Phase Variation

    Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
    The recognition sites for Cre recombinase called LoxP...
    5.7K
    Synteny and Evolution02:31

    Synteny and Evolution

    John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
    Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
    2.9K
    Exon Recombination02:32

    Exon Recombination

    The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
    Exon shuffling follows “splice frame rules.” Each exon...
    3.1K
    Crossing Over01:30

    Crossing Over

    Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I,...
    6.3K