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若い成人女性の尿路感染症は,Staphylococcus saprophyticusによって引き起こされる
JAMA
|December 9, 1983
まとめ
Staphylococcus saprophyticusは,大学生女性の尿路感染症 (UTIs) の一般的な原因であり,しばしばEscherichia coliのUTIsに類似して提示されます. 抗生物質に対する感受性にもかかわらず,再発するS. saprophyticusの尿路感染症が発生し,医師の意識が必要になります.
科学分野:
- 泌尿器科 泌尿器科とは
- 感染症 感染症は感染症です.
- 微生物学 微生物学とは
背景:
- 尿路感染症 (UTI) は,特に大学年齢の女性の間で一般的です.
- エシェリキア・コライは,尿路感染症の最も頻繁な病原体です.
- この集団におけるUTI病原体としてのStaphylococcus saprophyticusの役割については,さらなる理解が必要である.
研究 の 目的:
- 大学女子における,Staphylococcus saprophyticusによる尿路感染症の臨床的特徴とアウトカムを,Escherichia coliと比較する.
- S. saprophyticusの尿路感染症の局所化と植民地化パターンを調査する.
- S. saprophyticusのインビトロ抗菌感受性を評価し,治療結果を評価する.
主な方法:
- 72人の大学生女性におけるS. saprophyticusによって引き起こされた81件の尿路感染症と,E. coliによる尿路感染症を比較した後の評価.
- 患者の人口統計,尿路感染症の病歴,臨床表現,尿検査の結果の分析.
- 感染の局所化と微生物のコロニー化 (直腸,陰道,尿道) の評価のための抗体コーティング細菌技術の適用.
- S. saprophyticusの単離物のインビトロ抗菌感受性試験
主要な成果:
- S. saprophyticusは,研究期間中に尿路感染症の11%を占め,夏の終わりと秋の初めの季節的な流行がありました.
- S. saprophyticus と E. coli の尿道感染症の臨床表現と尿分析結果は類似していました.
- S. saprophyticusの尿路感染症は,より頻繁に尿路上部に局限していた (41%対16%,P = .01).
- 下部生殖器管の植民地化は,S. saprophyticusの尿路感染症と関連しており,E. coliの尿路感染症と同様の病原性を示唆しています.
- 一般的な抗菌剤に対するインビトロ感受性にもかかわらず,再発性S. saprophyticus感染症は72人の女性のうち6人に発生しました.
結論:
- Staphylococcus saprophyticusは,若い女性における尿路感染症の重要かつ一般的な原因である.
- 医師や微生物学者は,重要な尿路感染症の病原体としてS. saprophyticusを認識する必要があります.
- S. saprophyticusの尿路感染症の病原性は,E. coliの尿路感染症と似ており,コロニー化を伴う可能性があります.
- S. saprophyticusの尿路感染症の再発は,適切な抗菌薬療法にもかかわらず起こりうるため,管理における潜在的な課題を強調しています.
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