関連する実験動画

Updated: Aug 4, 2026

Silicon Microchips for Manipulating Cell-cell Interaction
23:21

Silicon Microchips for Manipulating Cell-cell Interaction

Published on: August 30, 2007

カルシウムに依存する細胞-細胞粘着系は,マウスの発達初期に細胞内質量形成と細胞表面の極化を調節する

Y Shirayoshi, T S Okada, M Takeichi

    Cell
    |December 1, 1983
    PubMed
    まとめ

    モノクローナル抗体ECCD-1は,初期のマウス胚におけるカルシウム依存性細胞結合を阻害し,細胞内部の質量形成を防ぐ. これは,胚の発達に不可欠な細胞表面の極化に影響を与えます.

    さらに関連する動画

    Mouse Fetal Whole Intestine Culture System for Ex Vivo Manipulation of Signaling Pathways and Three-dimensional Live Imaging of Villus Development06:46

    Mouse Fetal Whole Intestine Culture System for Ex Vivo Manipulation of Signaling Pathways and Three-dimensional Live Imaging of Villus Development

    Published on: September 4, 2014

    Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation07:30

    Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation

    Published on: June 28, 2024

    関連する概念動画

    Determination01:51

    Determination

    During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In contrast, determination...
    Cells Coordinate Growth and Proliferation02:36

    Cells Coordinate Growth and Proliferation

    Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
    Cell Motility through Blebbing01:16

    Cell Motility through Blebbing

    Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
    Blebbing Through the Matrix
    In multicellular...
    Mechanisms of Membrane Domain Formation00:59

    Mechanisms of Membrane Domain Formation

    Different physical properties of lipids and proteins allow them to localize and form distinct islands or domains in the membrane. Some membrane domains are formed due to protein-protein interactions, whereas others are formed due to the presence of specific lipids such as sphingolipids and sterols—for example, large proteins, such as bacteriorhodopsin, aggregate and create distinct domains.
    Another mechanism for membrane domain formation involves membrane proteins interacting with cytoskeletal...
    Overview of Cell-Matrix Interactions01:24

    Overview of Cell-Matrix Interactions

    The extracellular matrix or ECM holds cells together to form a tissue and allows the cells within the tissue to communicate. ECM comprises proteins such as fibronectin, collagen, laminin, etc. The most abundant protein in this space is collagen. Collagen fibers are interwoven with carbohydrate-containing protein molecules called proteoglycans. ECM allows cell migration and provides a structural scaffold at cell adhesion that anchors the cell when the extracellular matrix proteins interact with...
    Cell Adhesion Molecules - Types and Functions01:20

    Cell Adhesion Molecules - Types and Functions

    Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
    CAM Families
    The Integrin family of proteins is primarily  involved in a...