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Updated: Aug 5, 2026

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies
04:47

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies

Published on: February 23, 2018

抗体のセグメンタル・フレキシビリティとエフェクター機能の相関関係

V T Oi, T M Vuong, R Hardy

    Nature
    |January 12, 1984
    PubMed
    まとめ

    研究者らは,ダンシルを標的としたマウスのモノクローナル抗体を生成し,免疫グロブリン同型がエフェクター機能に影響することを発見しました. 抗体の柔軟性と補完体の固定性は変化しており,Fabの腕の動きがこれらの機能に影響することを示唆しています.

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