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Updated: Aug 17, 2026

Assessing Somatic Hypermutation in Ramos B Cells after Overexpression or Knockdown of Specific Genes
08:12

Assessing Somatic Hypermutation in Ramos B Cells after Overexpression or Knockdown of Specific Genes

Published on: November 1, 2011

免疫グロブリン重鎖スイッチにおける遺伝子消去の役割

T H Rabbitts, A Forster, W Dunnick

    Nature
    |January 24, 1980
    PubMed
    まとめ

    マウスの重鎖亜種における遺伝子の再編成と消去は,H鎖スイッチのメカニズムを示唆する. この研究では,マウスの免疫細胞におけるIgG2b,IgG2a,IgG1の遺伝子配列を調べています.

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