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Updated: Jul 10, 2026

Using SecM Arrest Sequence as a Tool to Isolate Ribosome Bound Polypeptides
09:42

Using SecM Arrest Sequence as a Tool to Isolate Ribosome Bound Polypeptides

Published on: June 19, 2012

シグナルシーケンスだけでは,β-ガラクトシダースを細胞プラズマから誘導するには不十分です

F Moreno, A V Fowler, M Hall

    Nature
    |July 24, 1980
    PubMed
    まとめ

    研究者らは,lacZ遺伝子 (β-ガラクトシダゼ) とlamB遺伝子 (外膜タンパク質) を融合させ,Escherichia coli菌株を設計した. 重要な発見は,ベータ-ガラクソシダースは,lamB信号配列を含んでいるにもかかわらず,細胞質のままであることです.

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