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Updated: Aug 19, 2026

Assessing Somatic Hypermutation in Ramos B Cells after Overexpression or Knockdown of Specific Genes
08:12

Assessing Somatic Hypermutation in Ramos B Cells after Overexpression or Knockdown of Specific Genes

Published on: November 1, 2011

免疫グロブリン欠損変異体で,重鎖スイッチとRNAスプライシングに影響を及ぼします

W Dunnick, T H Rabbitts, C Milstein

    Nature
    |August 14, 1980
    PubMed
    まとめ

    IF2免疫グロブリン変異体はDNAの消去を伴い,新しいスプライシングパターンを生み出します. この変異は,重鎖のクラス・スイッチ・シグナルと潜在的に結びついているタンデム・リピートを持つDNAに由来する.

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