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Updated: May 8, 2026

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
15:07

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

Published on: December 28, 2015

Bリンパ球の微分化の異なる段階を表す細胞系におけるJ鎖RNAの発現

E L Mather, F W Alt, A L Bothwell

    Cell
    |February 1, 1981
    PubMed
    まとめ

    J鎖合成は,IgM分泌のためのB細胞の分化中に開始されます. この研究では,J鎖RNAが分泌するプラズマ細胞に検出されたが,未差別化されたB細胞には検出されなかったため,抗原/ミトゲンがRNA発現または安定化を誘発することを示唆した.

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