心筋梗塞の患者における左心房機能の重要性

Y Matsuda, Y Toma, H Ogawa

Circulation

|March 1, 1983

まとめ

前回の心筋梗塞を患った患者は,左心房機能の増加を示し,より大きな心房作業と空化を含む. この補償機構は,フランク・スターリング機構を通じて左心室の機能を助けます.

科学分野:

心臓病学心臓病学
心臓生理学心臓生理学
心筋梗塞の研究

背景:

左心房機能は,心臓の全般的な機能に重要な役割を果たします.
遠隔心筋梗塞は,心臓のメカニズムと血液動力学を変えることができます.
心房内の補償メカニズムを理解することは,心筋梗塞後の患者の管理に不可欠です.

研究の目的:

心筋梗塞の anamnesis を有するおよび無する患者の左心房機能を評価し,比較するために.
左心房機能と心筋梗塞後の左心房機能の関係を調査する.
心筋梗塞後の左心房におけるフランク・スターリング機構の役割を決定する.

主な方法:

カテーテルチップマイクロマノメーターを用いた左心房圧の同時記録.
左心房と左心室のシネアニオグラムの取得.
左心房の圧力-体積曲線 (AループとVループ) の構築.

主要な成果:

リモート心筋梗塞の患者は,左心室脳卒中の容量に対するアクティブな心房空化の比率 (42%対29%) が著しく高かった.
左心房の働きは,心筋梗塞の患者に著しく増加した (1690 vs 940 mm Hg x ml).
左心房の働きは左心房の体積と正に相関し,左心房の放出分数と逆に相関した.

結論:

左心房は,リモート心筋梗塞の患者の左心室機能への貢献が増加していることを示しています.
この増加した心房の寄与は,左心房内のフランク・スターリング機構によって媒介される可能性が高い.
この発見は,心筋梗塞後の心臓の出力を維持する左心房の補償的役割を強調しています.

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