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Updated: Jul 23, 2026

Evaluating In Vitro DNA Damage Using Comet Assay
10:43

Evaluating In Vitro DNA Damage Using Comet Assay

Published on: October 11, 2017

化学的発がん物質によるDNAメチル化の阻害 in vitro

V L Wilson, P A Jones

    Cell
    |January 1, 1983
    PubMed
    まとめ

    化学的発がん物質は,マウスのメチルトランスフェラーゼを阻害し,酵素を直接損傷することにより,DNAメチル化を妨げます. これは,細胞内の5メチルサイトシンパターンの遺伝的変化につながる可能性があります.

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    Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter12:15

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