輸血による死亡者

B A Myhre

JAMA

|September 19, 1980

まとめ

1976年から1979年の研究では,輸血関連の死亡例が113件見つかった. ほとんどの死亡は事務上の誤りによるもので,輸血後の肝炎や実験室での誤りも患者の被害に寄与した.

科学分野:

輸血医学とは
患者の安全性について
肝炎研究肝炎に関する研究

背景:

輸血は重要な医療処置である.
輸血に関連する有害事象は,継続的なモニタリングを必要とします.
食品医薬品局 (FDA) は,輸血関連の死亡者に関するデータを収集しています.

研究の目的:

1976年から1979年の間に輸血を受けた後にFDAに報告された死亡者数を分析する.
輸血による死亡の原因を分類する.
輸血の安全性を改善すべき分野を特定する.

主な方法:

FDAに提出された死亡報告の遡及的分析.
特定された原因に基づいて報告された死亡の分類.
1976年4月3日から1979年12月31日までのデータのレビュー

主要な成果:

合計で113人の死亡者が報告されました.
33人の死亡は輸血後の肝炎に起因した.
47例 (61%) の死亡は"事務上の誤り" (例えば,間違った血液型が投与されたこと) に起因した.
8人の死亡は,実験室の誤りによるものです.
22人の死亡は,様々な原因で発生し,多くの場合,予防できませんでした.

結論:

事務上の誤差は,輸血関連の死亡の重要な原因であり,予防可能である.
輸血後の肝炎は懸念事項であり続けていますが,誤りよりも潜在的に頻度は低いです.
継続的な警戒とエラー削減戦略は,輸血の安全性の向上に不可欠です.

さらに関連する動画

10:32

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination

Published on: August 24, 2015

05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

関連する概念動画

02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...

01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...

01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...