レシチン摂取は,血清のフリーコレンのレベルを上昇させます
Lancet (London, England)
|July 9, 1977
まとめ
口服レシチンは,塩化コリンよりも効果的に血清のコレンのレベルを大幅に上昇させます. これは,コレンの可用性を高めることによってアセチルコリン合成を促進するための好ましい方法である可能性を示唆しています.
科学分野:
- 神経科学は神経科学である.
- バイオケミストリー バイオケミストリー
- 人間の栄養 ヒトの栄養
背景:
- コリン摂取は血清と脳コリンを増加させ,アセチルコリンレベルに影響を与えます.
- コリン投与は,遅発性不運動症の認められた治療法である.
- 最適なコレンの配達方法を理解することは,神経学的健康にとって極めて重要です.
研究 の 目的:
- ヒトの血清コレンのレベルを上昇させるための経口レシチンとコレンの塩化物の有効性を比較する.
- アセチルコリン合成の前駆体としてのコレンの可用性に対するレシチンの影響を評価する.
主な方法:
- ヒトの被験者は,コリン塩化物またはレチチンの標準投与量を摂取した.
- 血清コレンのレベルは,摂取後の様々な時間点で測定されました.
- 血清コレンの上昇の期間と大きさを分析した.
主要な成果:
- レシチン摂取は1時間以内に血清コレンの濃度が265%上昇し,12時間持続した.
- コリン塩化物の摂取により,血清のコリン濃度が30分以内に86%上昇し,4時間以内に正常化しました.
- レシチンは,コリン塩化物と比較して,血清コレンのより優れ,より持続的な上昇を示した.
結論:
- 経口用レシチンは,ヒトの血清コレンの濃度を上昇させるのに,コリン塩化物よりも有意に効果的です.
- レシチンは,アセチルコリンの前駆体であるコレンの可用性を高めるための潜在的に優れた方法を表しています.
- この発見は,治療目的でアセチルコリン合成を促進することを目的とした戦略に意味を持っています.
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