シストリック血圧,動脈の硬直,脳卒中のリスク. フレミングハム研究によると,

W B Kannel, P A Wolf, D L McGee

JAMA

|March 27, 1981

まとめ

孤立したシストリック高血圧は,動脈の硬さとは関係なく,脳卒中のリスクを大幅に増加させます. この状態は,年齢とともにより一般的になり,正常な血圧と比較して,脳卒中の発生率を2倍から4倍にします.

科学分野:

心血管医学は,心臓血管医学である.
神経学神経学とは
エピデミオロジーエピデミオロジー

背景:

高血圧は脳卒中の主要な危険因子です.
隔離性シストリック高血圧 (ISH) は,高齢者の間で一般的です.
ISH,動脈硬化,脳卒中リスクの関係については,さらなる解明が必要である.

研究の目的:

孤立したシストリック高血圧と脳卒中の発生率との関連を調査する.
動脈硬直とは無関係にISHが脳卒中を誘発するかどうかを判断する.
ISHと脳卒中リスクにおける年齢とパルス波構成の役割を評価する.

主な方法:

フレミングハム研究からの将来的なデータ分析.
静心圧,静心圧,年齢,パルス波構成の評価.
ISHの被験者における脳卒中発生率の比較と,正常血圧の個体との比較.

主要な成果:

孤立した静脈性高血圧は,動脈硬直とは無関係に脳卒中を誘発する.
ISHの罹患率は,年齢とともに増加し,二角突起の鈍化に伴います.
ISH患者の脳卒中発生率は,正常血圧患者より2~4倍高かった.
静脈圧は,高血圧患者の脳卒中リスク評価にほとんど貢献しなかった.

結論:

孤立したシストリック高血圧は,脳卒中の重要な独立リスク因子です.
年齢とパルス波の特徴は,ISHと関連しています.
静脈動脈圧は,ISH患者の脳卒中リスク予測において最小限の役割を果たします.

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