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Updated: May 12, 2026

Efficient Gene Transfer in Chick Retinas for Primary Cell Culture Studies: An Ex-ovo Electroporation Approach
08:59

Efficient Gene Transfer in Chick Retinas for Primary Cell Culture Studies: An Ex-ovo Electroporation Approach

Published on: November 2, 2015

遺伝子の進化:鶏のプリプロインスリン遺伝子

F Perler, A Efstratiadis, P Lomedico

    Cell
    |June 1, 1980
    PubMed
    まとめ

    鶏とネズミのインスリン遺伝子構造は,進化の洞察を明らかにします. 非コーディングDNAの急速な変化がそう示唆している.

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    The Central Dogma

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    Gene Duplication and Divergence02:37

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    The Central Dogma01:20

    The Central Dogma

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    Insulin: Biosynthesis, Chemistry, and Preparation01:25

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    The endoplasmic reticulum (ER) of pancreatic β-cells synthesizes preproinsulin, which consists of a signal peptide, A and B chains, and a C-peptide. Preproinsulin is then cleaved and folded into proinsulin, which translocates to the Golgi apparatus for sorting and packaging into secretory granules. In these granules, enzymatic clipping generates insulin and C-peptide.
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