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Updated: Jul 19, 2026

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
08:53

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 17, 2011

乳がんにおけるBRCA1の異常なサブセルラー局所化

Y Chen1, C F Chen, D J Riley

  • 1Center for Molecular Medicine/Institute of Biotechnology, University of Texas Health Science Center at San Antonio 78245, USA.

Science (New York, N.Y.)
|November 3, 1995
PubMed
まとめ

BRCA1遺伝子の産物である正常細胞の核フォスフォタンパク質は,多くの乳がんや卵巣がんでは細胞質に移行する. この異常な位置は,BRCA1の異常が乳がんの発症に寄与することを示唆しています.

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