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Updated: Aug 5, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
12:09

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

MHCIIクラス分子に結合する内生性エピトープの多様性は,不変鎖によって制限されます

H Bodmer1, S Viville, C Benoist

  • 1Laboratoire de Génétique Moléculaire des Eucaryotes du CNRS, Strasbourg, France.

Science (New York, N.Y.)
|March 4, 1994
PubMed
まとめ

インヴァリアントチェーン (II) は,メジャー・ヒストコンパティビリティ・コンプレックス (MHC) クラスIIのプレゼンテーションを調節し,時にはエピトープをブロックし,時には必要とする. これは抗原プレゼンテーションに影響を及ぼし,自己免疫に関連している可能性があります.

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Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis09:32

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