関連する実験動画

Updated: Jul 18, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
11:44

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

転写因子Stat91のインターフェロンの活性化には,SH2-フォスフォチロシルペプチド相互作用による二分化が含まれます

K Shuai1, C M Horvath, L H Huang

  • 1Laboratory of Molecular Cell Biology, Rockefeller University, New York, New York 10021.

Cell
|March 11, 1994
PubMed
まとめ

シグナルトランスデューサーとトランスクリプションのアクティベーター91 (Stat91) モノメアは,インターフェロン-ガンマ刺激で二元化します. SH2-フォスフォチロシル相互作用によって媒介されるこのStat91二分化は,DNA結合と遺伝子転写に不可欠です.

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Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization08:57

Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization

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