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Updated: Aug 14, 2026

Preparation and Use of HIV-1 Infected Primary CD4+ T-Cells as Target Cells in Natural Killer Cell Cytotoxic Assays
12:07

Preparation and Use of HIV-1 Infected Primary CD4+ T-Cells as Target Cells in Natural Killer Cell Cytotoxic Assays

Published on: March 14, 2011

細胞毒性T細胞活動が,自然に発生するHIV-1ガグの変異体によって逆らわれる

P Klenerman1, S Rowland-Jones, S McAdam

  • 1Nuffield Department of Clinical Medicine, University of Oxford, UK.

Nature
|June 2, 1994
PubMed
まとめ

自然に発生するHIV-1ガグエピトープの変種は,細胞毒性Tリンパ球 (CTL) 反応を損なう可能性があります. これらのウイルスの突然変異は,合成ペプチドによって提示された場合でも,敵対性を引き起こし,免疫システムを低下させます.

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